The European Commission has decided not to approve caffeine (1,3,7-trimethylxanthine) as a basic substance. This decision was based on safety concerns for human health and environmental impact. The European Food Safety Authority (EFSA) identified risks including harmful effects on human health, such as cardiovascular and neurological impacts, as well as inadequate data to ensure non-dietary safety. Additionally, potential environmental contamination, including drinking water and surface water exposure, was deemed significant. Despite further data provided by the applicant, the Commission concluded that the approval conditions were unmet.
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European Union
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European Union